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Trifexis Chewable for Dogs

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Trifexis Chewable for Dogs - 1 Dose - 61 lbs and up
$27.99 $19.99
Trifexis Chewable for Dogs - 3 Doses - 5-10 Lbs
$58.99 $49.99
Trifexis Chewable for Dogs - 6 Doses - 5-10 Lbs
$102.99 $93.99

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Trifexis Chewable

Trifexis is a chewable tablet used to terminate internal and external parasites. This product is labeled for use in puppies over 8 weeks of age and adults over five pounds.

How it Works
Trifexis begins working in 30 minutes, using its active ingredient Spinosad to kill biting fleas. This product not only kills biting fleas but their eggs as well, breaking the flea life cycle. Within four hours Trifexis terminates fleas and the microfilaria which mature into heartworms.

Trifexis terminates fleas, adult hookworms, immature roundworms, and adult whipworms.

Two common fleas infest our pets; the cat flea (Ctenocephalides felis) and the dog flea (Ctenocephalides canis). Fleas live both indoors and out, following the pet and infecting said pet at different stages of life. There are four stages in a flea’s life: egg, larva or caterpillar, cocoon, and adult. The larvae grow and form a cocoon around them which is highly resistant to the environment, making them difficult to terminate. This larva can survive quite a long time in their cocoons and only hatch with the presence of carbon dioxide is present, which is the exhalant gas, produced from the body. Fleas attach themselves to pets in order to consume their blood. As these tiny pests take their blood meals, the skin inflames causing pets to itch and scratch excessively. Pet owners may not be able to view the fleas themselves but will be able to view a product known as flea dander. Flea dander appears as black dirt within the pet’s hair, this so called dirt is in fact digested blood defecated by the flea.

Heartworms or Dirofilaria immitits, are a species of roundworms classified in a group called nematodes. Heartworms are a parasite, which means they need a viable host to thrive, living out there lives feeding and reproducing in the organs of warm blooded mammals. Heartworms are actually transmitted to a pet through the bite of a mosquito. The flora of the heartworm lives within the mosquito until said mosquito takes his blood meal, injecting the roundworm in the process. These heartworms mature, reproduce, and thrive in the hearts of our pets. A pet with heartworm disease will become intolerant to exercise, cough, and may display drowsiness. In severe cases of this disease a pet may pass or collapse due to inadequate blood flow.

As a pet owner, it is difficult to prevent external parasitic infestation during warm months. In order to keep your pet’s healthy; dedication to treatments and proper care is a must. Pet aliments caused by ticks can be wide ranging and include fever, swelling in the joints, loss of appetite, pain in body or limbs and difficulty in walking. Additional ailments cause by these external pests include; anemia, lethargy, purities, hairless, and weight loss.


Fleas and heartworms affect all breeds of cats as well as dogs. Two common fleas infest our pets; the cat flea (Ctenocephalides felis) and the dog flea (Ctenocephalides canis). Adult fleas are tiny, just 1-5 mm in size having flat bodies and feed on animals’ blood.


1.What steps should I take if my pet has adverse effects from product?
Stop use and contact your veterinarian immediately. Adverse side effects will be noted within an hour after administration.

2. IS this product approved by the FDA?
Yes, FDA approved to be purchased by a veterinarian.

3. Is Trifexis a safe product?
Trifexis should not be used in puppies under 8 weeks of age. Pets must also weight over 5 pounds of body weight or greater up to 120 pounds.

4. What side effects should I be aware of while administering this product?
Vomiting, ear redness, skin inflammation, diarrhea, and itching.

5. Will this product work efficiently to terminate fleas and heartworms?
Yes, Trifexis kills 100% of biting fleas and heartworms.

6. Is Trifexis given year round?
Trifexis is administered based upon your geographic area. Pets residing in warm locations will require year round treatment due to the constant exposure to fleas and mosquitoes. Colder areas may not require long term treatment.

7. What flavors does this product come in?
Beef and pork.

8. Will Trifexis repel ticks as well?

9. Will this product kill existing heartworms?
No. Trifexis is a preventative medication which will terminate flora carried by mosquitos’ bites. Speak with your veterinarian about additional product to kill heartworms.

Product Cautions
The product must not be accessible to children.
This product is meant to be used for puppies, dogs, kittens and cats only.
Go through the entire content of the label before each use.
It can be hazardous to animals and humans and must be handled strictly as per instructions and dosages mentioned in the label.
Animals: Trifexis should not be used in puppies under 8 weeks of age. Pets must also weight over 5 pounds of body weight or greater up to 120 pounds.
Humans: It is injurious to ingest the contents. Care should be taken to avoid feed, water, and food contamination. Wash hands after use.
If Swallowed: Immediately contact a poison control center and seek advice. If the affected person is in a state to swallow, offer them to sip a glass of water. Unless suggested by the doctor at poison control centre, do not encourage the person to vomit. If the affected becomes unconscious, do not administer anything though their mouth.
Storage & Disposal
Storage: Store product between 20-25 degrees Celsius. Prevent contamination of food, water, or feed during storage and disposal. The contents should not be transferred to other containers.
Disposal: Empty containers should not be reused. Consign it to trash or look to the possibility of its recycling. Unused or leftover of the container should never be disposed in any drain.

Spinosad and Milbemycin oxime is the generic form of Trifexis. Generic form of this product terminates all adult biting fleas, eggs, and microfilaria of heartworms. Generic form is available as tablet formation at a slightly lower price than brand name.


Federal law makes it mandatory for the user to use the product strictly as per the instructions contained in the packaging.

Dogs and Cats:
Administer product orally, once a month.
Administer tablet with food for full effect.
Administer one tablet monthly for three months after mosquito’s exposure.
Vomiting may occur after administration. Continue to monitor pet for one hour after administration. Give second dose if vomiting occurs.

Dosage Schedule:
Body Weight    Spinosad Per Tablet (mg)    Milbemycin oxime Per Tablet (mg)    Tablets Administered       
5 to 10 lbs                     140                                                2.3                                               One       
10.1 to 20 lbs                270                                                4.5                                               One       
20.1 to 40 lbs                560                                                9.3                                               One       
40.1 to 60 lbs                810                                              13.5                                               One       
60.1 to 120 lbs            1620                                              27                                                  One       
Over 120 lbs    Administer the appropriate combination of tablets    



Active ingredients include Spinosad and Milbemycin oxime.

Recent Customer Reviews:  (1)
Rated 5/5 based on 1 customer reviews


SEPTEMBER 09, 2015

REVIEWER: Don't order from this company - by 

Ordered a 6-pill pkg for my dog; they didn't have 6 pills, only 5 so they charged me for the 5 pills at the "per pill" price (versus the 6-pill pkg price). Then was rude when I called them out on it!!