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Panacur Paste 10% indicated for the control of large strongyles (Strongylus edentatus S. equinus S. vulgaris) encysted early third stage (hyobiotic) late third stage and fourth stage cyathostome larvae small strongyles pinworms (Oxyuris equi) ascarids (Parascaris equorum) and arteritis caused by fourth stage larvae of Strongylus vulgaris in horses.Panacur (fenbendazole) Paste 10% is approved for use concomitantly with an approved form of trichlorfon. Thichlorfon is approved for the treatment of stomach bots (Gasterohilus spp.) in horses. Refer to the manufacturer's label for directions for use and cautions for trichlorfon.

CONTRAINDICATIONS: There are no known contraindications for the use of Panacur (fenbendazole) Paste 10% in horses.

DOSAGE: Panacur (fenbendazole) Paste 10% is administered orally at a rate of 2.3 mg/lb (5mg/kg) for the control of large strongyles small strongyles and pinworms. One syringe will deworm a 1 100 lb horse. For foals and weanlings (less than 18 months of age) where ascarids are a common problem the recommended dose is 4.6 mg/lb (10 mg/kg); one syringe will deworm a 550 lb horse. For control of encysted early third stage (hypobiotic) late third stage and fourth stage cyathostome larvae and fourth stage larvae of Strongylus vulgaris the recommended dose is 4.6 mg/lb (10 mg/kg) for 5 consecutive days; administer one syringe for each 550 lbs of body weight per day.

DIRECTIONS: 1. Determine the weight of the horse. 2. Remove syringe tip. 3. Turn the dial ring until the edge of the ring nearest the tip lines up with zero. 4. Depress plunger to advance paste to tip. 5. Now set the dial ring at the graduation nearest the weight of the horse (do not underdose). 6. Horse's mouth must be free of food. 7. Insert nozzle of syringe through the interdental space and deposit the paste on the back of the tongue by depressing the plunger.

CAUTION(S): Side effects associated with Panacur (fenbendazole) Paste 10% could not be established in well-controlled safety studies in horses with single doses as high as 454 mg/lb (1000mg/kg) and 15 consecutive daily doses of 22.7 mg/lb (50 mg/kg). Particularly with higher doses the lethal action of fenbendazole may cause the release of antigens by the dying parasites. This phenomenon may result in either a local or systemic hypersensitive reaction. As with any drug these reactions should be treated symptomatically. Panacur (fenbendazole) Paste 10% has been evaluated for safety in pregnant mares during all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproductivity were detected. The recommended dose for control of fourth stage larvae of Strongylus vulgaris 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days has not been evaluated for safety in stallions or pregnant mares.