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Methocarbamol is indicated as an adjunct to therapy of acute inflammatory and traumatic conditions of the skeletal muscle and to reduce muscular spasms. The efficacy of both tablets and injectable in the treatment of acute skeletal muscle hyperactivity.

Methocarbamol is a potent skeletal muscle relaxant which has an unusually selective action on the central nervous system, specifically on the internuncial neurons of the spinal cord. This specific action results in a diminution of skeletal muscle hyperactivity without concomitant alteration in normal muscle tone. Methocarbamol is long-acting and essentially non-toxic, and has proved effective in a wide range of disorders involving acute muscle spasm.