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Lysodren (mitotane)

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PRODUCT INFO
LYS1 Lysodren (mitotane) is a suppressant medication of the adrenal glands. As this product suppresses adrenal gland function, the cortisol hormone is also suppressed. This product is veterinary prescribed to be used in dogs.

WHAT THIS PRODUCT CURES
LYS1 Lysodren (mitotane) is used to treat Cushing’s disease.
PET SYMPTOMS


endocrine.jpgCushing’s disease refers to the over production of the hormone cortisol. Cortisol is administered into the body by paired glands in coordinate with the kidneys called the adrenals. Cortisol is a hormone which is released to regulate metabolism, immune responses, and blood increase of sugars. The adrenal glands are regulated by a portion of the brain called the hypothalamus. The hypothalamus delivers messages to the adrenal glands to produce more or less of its producing hormones. The adrenal glands release two hormones in particular along with cortisol; the two hormones normally produced by the adrenal glands, Mineralocorticoids and glucocorticoids, which are located, near the kidneys. Both of these hormones are critical to the healthy functioning of the body, and an abnormal increase or decrease of either of these hormones can lead to serious health problems if not addressed in time.

Cushing’s disease can be life-threatening and there are a variety of symptoms that can be present in many cases. The symptoms of Cushing’s disease include: anorexia, lethargy, weight loss, vomiting, shaking, diarrhea, polyuria (increased urination frequency), depression, polydipsia (increased thirst), dehydration, collapsing episodes, weak pulse, low temperature, hair loss, blood in the feces, and painfulness in the abdomen.
PET AILMENTS

Pet aliments associated with Cushing’s disease include: anorexia, lethargy, weight loss, vomiting, shaking, diarrhea, polyuria (increased urination frequency), depression, polydipsia (increased thirst), dehydration, collapsing episodes, weak pulse, low temperature, hair loss, blood in the feces, and painfulness in the abdomen.

PETS WITH ALIMENTS

RELATIVE INFO ON BREED MOST ASSOCIATED WITH THIS AILMENT
Cushing’s disease occurs for unknown reasons. Veterinary professionals have noted the disease occurs in older aged dogs, some with health problems. No breed of dog is directly connected to this disease as tumors can occur in any pet.

QUESTIONS FOR MY VET

1.What do I do if my pet has adverse effects from product?

        Contact an emergency veterinary center promptly.

2. What side effects could affect my pet while administering this product?

      The most common adverse reactions reported are weakness, diarrhea, lethargy, reduced      appetite, and poor hair coat.

3. What signs should I watch for in an overdose?

      Overdose side effects include; collapse, vomiting, and lethargy.

4. How should I protect myself while administering this product to my pet?

Do not handle medication if you are pregnant. Wear protective clothing such as gloves while handling medication. Wash hands with soap and water after administration.

5. What dogs should not take Lysodren?

Those who are pregnant, or those with kidney or liver failure should not take this product.
6. What happens if I miss a dose?

      Administer the dose as soon as you remember, but never give two doses in one day.

7. Is this product approved by the FDA?

       Yes, FDA approved to be purchased by a veterinarian.

8. What kind of diagnostic tests will be taken by the veterinarian before use?

The veterinarian will want to know the hormone levels produced by the adrenal glands; therefore, a complete chemistry panel will be conducted. This test requires a small sample of blood from your dog.
9. If Cushing’s disease is in fact a disease, can it ever be cured?

No disease can be 100% cured but it can be managed and increase the life of your pet.
10. Aside from administering Lysodren to aid my pet’s condition, what else will need to be changed in my pet’s lifestyle?

Your pet’s daily routine will not change much. The veterinarian may prescribe a different formula of food specific to the disease.

Product Cautions

The product must not be accessible to children.

This product is not to be handled by pregnant individuals.

This product is meant to be used for dogs only.

Go through the entire content of the label before each use.

It can be hazardous to animals and humans and must be handled strictly as per instructions and dosages mentioned in the label.

Animals: Not to be used in pregnant or lactating females. To be used in dogs only, do not use product in felines.

Humans: It is injurious to inhale or swallow the contents. Avoid food and water contamination. After use, wash your hands thoroughly with water and soap. Do not handle this medication if you are pregnant.

PHYSICAL OR CHEMICAL HAZARDS:

FIRST AID

If Swallowed: Immediately contact a poison control center and seek advice. If the affected person is in a state to swallow, offer them to sip a glass of water. Unless suggested by the doctor at poison control centre, do not encourage the person to vomit. If the affected becomes unconscious, do not administer anything though their mouth.

If on skin or clothing: Immediately remove polluted clothing and keep washing the skin with liberal volumes of water for fifteen to twenty minutes. Approach a doctor or poison control centre for further advice and action to be taken.

Storage: Store product at room temperature away from light, heat sources, and moisture.

Disposal: Empty containers should not be reused. Consign it to trash or look to the possibility of its recycling. Unused or leftover of the container should never be disposed in any drain. Seek help of local solid waste agency or call up 1-800-CLEANUP1-800-CLEANUP for instructions concerning disposal.

BRAND VS GENERIC COMPARISON

The brand name of LYS1 Lysodren (mitotane) is Lysodren (Bristol-Myers Squibb) and the generic version is Mitotane. Generic and name brand medications contain the same active ingredient with slightly different costs and quantities.

 

How it Works

The top cranial portions of the adrenal glands produce the hormone corticosteroid. LYS1 Lysodren (mitotane) erodes said portions of the gland to prevent cortisol overload in the body.

   *Note improved hair coat and body condition in dog before and after treatment.
DIRECTIONS FOR USE:

To be administered orally. It is unlawful to administer drug in any way other than directed.

DOSAGE AND ADMINISTRATION:
Dogs:

Dosage varies from cases to case.

Follow veterinary instructions exactly.

To be used in Dogs only.

Initials does for first two weeks will be greater than the duration of treatment time.



Ingredients
 

Active Ingredients

Mitotane

500 mg

 

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