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Lutalyse - 30 ml
$26.99 $21.99
Lutalyse - 100 ml
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LUT1 Lutalyse, manufactured by Zoetis, is a sterile injectable solution of dinoprost tromethamine.

LUT1 Lutalyse is used in horses, swine, dairy and beef cattle to induce female estrous. Lutalyse is also used to treat subestrus, pyometra, and mummified fetus and to induce abortion.

 The estrous cycle or the heat cycle is the process of chemical changes occurring in animals of reproductive age. Cows and Pigs are classified as polyestrous animals, which means they continuously ovulate throughout the year. Cows and pigs go in and out of estrous every 21 days. Horses are referred to as seasonally polyestrus. This means they have breeding season in which they have multiple heat cycles and a period where they will not go into heat. Estrous is the point in time in which a female will accept a male for breeding. Females will begin to show estrous signs such as bellowing, secreting cervical mucus, standing to be mounted and the “toning” of the uterus that aids in transportation of semen at the time of insemination.

The ability to manage the estrous cycle of livestock is helpful for a variety of reasons. Primarily estrous management means control of the date in which a cow/pig/horse will have offspring. Livestock producers plan their livestock’s reproductive cycles to be able to have all animals produce at the same time, saving time, money, and avoiding problems. Additionally estrous induced in a pregnant female will cause abortion. Females which have been bred too young to birth safely or these bred by inappropriate partners may require abortion needs.

Livestock which require estrous stimulate can display pyometra aliments, abortion aliments, or inability to reach estrous. A pyometra is a pus filled uterus which will be viewed from the vulva. Abortions may be needed due to a fetus that has died. Aliments in which a fetus has died include mucus viewed from the vulva; the animal will develop a fever, foaming at the mouth, and sudden death.


This aliment is non-specific to any breed of horse, pig, or cow.


1.What should I do if my pet has adverse effects from product?
Discontinue use and contact your veterinarian immediately.

2. What are the possible side effects which could appear in my animal?
Sweating, increase in heart rate and some abdominal discomfort, but they pass off within half to one hour, without treatment.

3. How soon will Lutalyse take effect?
Dependant of the use of this product, owners should be able to see change within an hour.

4. I would like to artificially inseminate my horse, is Lutalyse a good choice?
Absolutely. Artificial insemination is a process in which semen in collected from a stallion and then placed in the uterus of a female by use of catheter. Using Lutalyse an owner can control the cycle instead of waiting for the female to go into heat.

5. I have used Lutalyse on my cow to abort the calf but it has been four hours and the calf is not out. What should I do?
Seek veterinary help immediately. The calf could possibly be turned around and unable to be pushed out. Call the vet immediacy and work to feel the calf in order to place the head towards the uterus.

Product Cautions

PET:  Do not administer LUTALYSE in pregnant cattle unless cessation of pregnancy is desired.

HUMANS: Women of childbearing age and persons with respiratory problems should exercise extreme caution when handling LUTALYSE.  LUTALYSE is readily absorbed through the skin and may cause abortion and/or bronchiospasms, therefore spillage on the skin should be washed off immediately with soap and water

If on skin or clothing: Immediately remove polluted clothing and keep washing the skin with liberal volumes of water for fifteen to twenty minutes. Approach a doctor or poison control centre for further advice and action to be taken.

Storage and disposal

Storage: Store at controlled room temperature between 15° and 25° C.

Disposal: Empty containers should be disposed of as directed and never re-used. Recycling or garbage disposal is viable as directed upon product label. Consult a medical waste agency for directions to depose of remaining drug and container. Contact 1-800-CLEANUP for additional information.

Dinoprost tromethamine is the generic name for Lutalyse. The generic brand is named after its active ingredient which is in Lutalyse as well.  


How it Works
Prostaglandins, which cause an animal to begin estrous, increase in the uterus and blood levels naturally by a chemical in the body. Lutalyse copies this chemical, producing the same effects as this naturally occurring hormone.  

How do I administer product intramuscularly?
Medications administered within the muscles are given in the rump or the meaty portion of the shoulder.
Locate a large muscles within designated area, firmly inject needle into the muscle. (the needle should not be visible)

Horses: To induce estrus, administer 5 mg (1 mL) subcutaneously.
Cattle: To control estrus, to treat subestrus, pyometra, and mummified fetus and to induce abortion or parturition administer 25 mg (5 mL) intramuscularly.
Porcine: To induce parturition administer 10 mg (2 mL) intramuscularly.

dinoprost tromethamine


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