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Glyco-Flex II is a nutritional supplement used for maintaining healthy joints. It comes in different formulations, chewable tablets for dogs (it is stage II of a comprehensive program for dogs - recommended for dogs with a moderate need for joint support, adult and maturing dogs, sporting and working breeds, as well as a follow-up to orthopedic surgery) and either as chewable tablets or soft chews for cats and small dogs (recommended for older cats and small dogs with greater need for joint support). All formulations contain glucosamine as well as Perna Canaliculus (green lipped mussel - which is a good source of protein, minerals, and chondroitin sulfates) and MSM. The tablets are natural imitation roast chicken flavored and the soft chews are chicken liver flavored. The active ingredients include glucosamine and Perna Canaliculus (green lipped mussel). Glucosamine is a natural compound that is found in healthy cartilage in both humans and pets. It helps hydrate healthy joints by increasing the production of molecules that bind and hold water in the cartilage. Healthy cartilage provides cushioning which helps protect a pet's joints while exercising. Many believe that it provides clinical benefit in the synovial fluid by strengthening cartilage and aiding glycosaminoglycan synthesis. Further research on the effectiveness of glucosamine is still needed, but many of our customers find it to be very beneficial to their pets. DIRECTIONS: The usual dose of Glyco-Flex II for Dogs for the first 4-6 weeks in dogs up to 30 lbs is 1/2 tablet. For dogs 31-60 lbs use 1 tablet, for dogs 61-100 lbs use 2 tablets and for dogs 101 lbs and over use 2 1/2 tablets. The maintenance dose for dogs up to 30 lbs is 1/2 tablet every other day, for dogs 31-60 lbs is 1/2 tablet, for dogs 61-100 lbs is 1 tablet, for dogs 101 lbs and over is 1 1/2 tablets daily. The usual dose of Glyco-Flex II for Cats and Small Dogs for the first 4-6 weeks in cats 1-8 lbs is 1 tablet daily. For cats over 8 lbs give 2 tablets daily. The maintenance dose in cats 1-8 lbs is 1/2 tablet daily, and for cats over 8 lbs give 1 tablet daily. The usual dose of Glyco-Flex II Soft Chews for Cats and Small Dogs for the first 4-6 weeks is 2 Soft Chews per 10 lbs of body weight, daily. After the initial period, give a maintenance dose of 1 Soft Chew per 10 lbs of body weight, daily. If giving more than 1 chew, divide between AM and PM. CAUTION(S): This product is for animal use in dogs only. Glucosamine, in humans, may increase insulin resistance and consequently affect glucose tolerance. Diabetic dogs or dogs that are overweight and have problems with glucose tolerance should have their blood sugars monitored if they are given glucosamine supplements. Store in a cool, dry, place. Keep out of the reach of children.