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Diphenhydramine is an antihistamine used in the treatment of allergies, insect bites or stings and other causes of itching. It is also used for its sedative and antiemetic effects in the treatment of motion sickness and travel anxiety. It is also used for its antitussive effect. It is available in 50mg capsules. DIRECTIONS: Diphenhydramine is FDA-approved for external use in dogs and cats. Oral diphenhydramine is not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs and cats. The usual dose in dogs and cats is 0.5-2mg/pound every 8-12 hours. The slow release capsule should not be mixed or dissolved in food. Do not give sinus or cold medicines containing diphenhydramine to your pet. SIDE EFFECT(S): of diphenhydramine include drowsiness, dry mouth and urinary retention. Rarely, vomiting and diarrhea can occur. CAUTION(S): Do not use this medication in animals that are allergic to it or other antihistamines. Do not use in animals with glaucoma, prostate disease, urinary obstruction, and high blood pressure. Do not use in pregnant or nursing animals. Use with caution when given with other CNS (central nervous system)-depressant drugs such as tranquilizers or barbiturates. Always tell your veterinarian and pharmacist what other medications your pet is taking. Keep out of reach of children. FOR ANIMAL USE ONLY.