Clomipramine is used to treat obsessive compulsive disorders and separation anxiety. It is available as 25mg, 50mg and 75mg capsules. The usual dose in dogs is 0.9-1.8mg/pound by mouth once a day with food. Clomipramine can also be used in cats and the usual dose is 0.5mg/pound by mouth once a day. Clomipramine (Clomicalm) is a tricyclic antidepressant that is FDA approved for veterinary use in dogs for the treatment of separation anxiety. Clomipramine (Anafranil), FDA approved for human use, is sometimes used in veterinary medicine to treat aggression and obsessive-compulsive disorders such as tail chasing.
Clomipramine is available as 25mg, 50mg and 75mg capsules; the dose varies according to the weight of the animal and the recommendation of the veterinarian. The usual dose in dogs is 0.9-1.8mg/pound by mouth once a day with food. Clomipramine can also be used in cats, and the usual dose is 0.5mg/pound by mouth once a day.
Clomipramine can cause numerous anticholinergic side effects. Anticholinergic side effects occur when Clomipramine restricts the involuntary functions caused by the neurotransmitter acetylcholine. Clomipramine should not be used to treat animals, which have hypersensitivity or allergy to the drug. The medicine should be used with extreme care in animals suffering from seizure disorder. Clomipramine should not be prescribed for animals having slow gastrointestinal tracts, heart rhythm abnormalities or cardiac arrhythmias and glaucoma (elevated pressure in the eye).
Certain precautions must be taken while the pet is being treated with Clomipramine. Animals suffering from liver impairment should be cautiously monitored with suitable blood tests while under medication. Clomipramine also has the possibility to interact with different kinds of medications including cimetidine, monoamine oxidase inhibitors and anti-thyroid medication. The most commonly found effects of clomipramine are inappetance (not eating enough), sedation and increased heart rate.