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This spot-on topical solution for use on dogs is the same formula as Frontline Plus® (fipronil and S-methoprene) with the addition of amitraz. The ingredients potentiate one another and work particularly well to kill ticks while maintaining a high level of long-lasting efficacy against adult fleas, eggs and larva. It is indicated for the treatment and prevention of infestations in dogs by ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes scapularis, Dermacentor variabilis, Haemaphysalis elliptica, Haemaphysalis longicornis, Amblyomma americanum and Amblyomma maculatum) and fleas (Ctenocephalides felis and Ctenocephalides canis), as well as treatment of infestations by chewing lice (Trichodectes canis).

Prevents environmental flea contamination by inhibiting the development of all immature flea stages. Eliminates fleas and ticks within 24 hours. One treatment prevents further infestations by both fleas and ticks for up to 5 weeks.