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Indications: Benazepril is used in the treatment of high blood pressure, in the treatment of congestive heart failure, and in the treatment of renal (kidney) protein loss in cats and dogs. Benazepril is in the ACE inhibitor class of medications, similar to enalapril.
Caution: Benazepril is inactive when it is consumed and must be activated into âbenazeprilatâ (its active form) by the liver. If the pet's liver is in failure and cannot reliably perform this conversion, an ACE inhibitor that does not require conversion can be used. Benazepril probably should not be used in patients with impaired kidney function. This medication should not be used in pregnancy or lactation. ACE inhibitors have been known to cause taste disturbances. Should your pet appear to lose its appetite, continue taking benazepril and consult with your veterinarian.
Drug Interactions: Benazepril is commonly used in combination with diuretics, especially furosemide. In this situation, monitoring kidney parameters is especially important as both these medications serve to decrease blood supply to the kidney as they support the heart. Should a heart failure crisis occur while a patient is on these two medications, contact your veterinarian immediately. Blood potassium levels can become dangerously high when benazepril is used with other medications that elevate blood potassium level. Such drugs might include: potassium supplements (Polycitra, or Urocit-K) or spironolactone (a potassium-sparing diuretic.)Benazepril is less effective when used with aspirin or other NSAIDs (Carboprofen, ibuprofen and ketoprofen).
Side Effects: Nausea, appetite loss, and/or diarrhea are sometimes observed with this medication. In some pets, these effects are severe enough to preclude the use of benazepril. If the side effects appear to be bothersome, consult with your veterinarin as soon as possible. In some pets, blood pressure can drop too low as the peripheral blood vessels are dilated. This manifests as listlessness and lethargy. Often the dose of benazepril can be modified should this side effect occur. Benazepril may lead to elevations in potassium blood levels. Should your pet appear to have a serious side effect, discontinue benazepril and immediately seeks emergency veterinary care.
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