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Allopurinol is a drug used to decrease the amount of uric acid that is produced in canines. Although the medication is not approved by the FDA for use in animals, it is commonly prescribed by veterinarians as off label use. It is available in 100mg and 300mg tablets.
What the product cures
Allopurinol aids in the prevention of bladder, kidney, and urethral stones that develop due to increased uric acid levels.
Urolithiasis is a condition that occurs when stones are formed in a dog’s urinary tract. Stones that develop with the help of uric acid are called urate stones and can affect the kidneys, ureters (tubes connected from bladder to kidneys), and bladder. Not all canines show signs of illness with the condition, but if there are symptoms, they are usually related to the urinary tract. Some of these include; trouble urinating, decreased urine output, bloody urine, whitish colored urine, and blockage (where the dog is unable to urinate).
Prescription medication is available to treat the condition as well as help prevent it from reoccurring. However, the chances of a stone forming may still be high. Surgery is also necessary when blockage occurs, at it can lead to serious complications if not treated promptly. Most vets recommend follow-up tests (radiograph, ultrasound imaging) about once every 4 months so that the stones can be caught and treated early on.
High levels of uric acid in the body can lead to health ailments in dogs such as; kidney stones, bladder stones, and urethral stones.
Pets with Ailments
Relative info on breed most associated with this ailment
Stones caused by uric acid can develop in any breed, but Yorkies, English Bulldogs, and Dalmatians are particularly at risk. Male dogs are also more likely to be affected by these stones than females, especially during the early adult stages.
Questions for the vet & product
1. Is there anything I should tell my vet before giving my dog Allopurinol?
Let your vet known if your dog has been diagnosed with renal disease or liver disease before starting treatment. You should also notify your vet if your pet is pregnant, nursing, or is taking any additional medication, vitamins, or supplements.
2. What should I do if a dose is skipped?
If it hasn’t been too long, give the missed dose right away; otherwise, wait until it is time for the next dose and continue giving the medication as scheduled. Do NOT give two doses at once in order to make up for the missed one.
3. What if I overdose my dog?
Take your pet to the nearest emergency veterinary clinic if you think you might have overdosed him/her.
4. Can there be any side effects with Allopurinol?
As with all drugs, there are possible side effects associated with Allopurinol. Less severe side effects to look out for include; decreased appetite, nausea, loose stools, lethargy, dizziness, and joint inflammation. If your pet experiences any of the previously listed symptoms, continue with treatment as directed and consult your vet as soon as possible. More serious side effects linked to the medication are; allergic reaction (trouble breathing, facial swelling, rash, etc.), bloody urine, painful urination, fever, arthritis, and vomiting. Seek immediate veterinary help if your dog shows signs of serious side effects.
5. Are there any medications that should be avoided?
Drugs that you should tell your vet about before giving Allopurinol to your pet and that should be avoided include; amoxicillin, ampicillin, azathioprine, thiazide, theophylline, cyclosporine, warfarin, and chemotherapeutic agents. Speak with your vet prior to starting your dog on any other medication/supplements.
Allopurinol is NOT recommended for young dogs.
Allopurinol is NOT for use in cats.
Give medication with food.
Provide clean water at all times throughout treatment.
Allopurinol may result in drowsiness.
Do NOT give to pregnant or lactating dogs.
Let your vet know if your pet has been diagnosed with a liver or renal condition before Allopurinol is prescribed.
Provide your vet with a list of all the drugs and supplements that your dog is taking before you start giving Allopurinol.
PHYSICAL OR CHEMICAL HAZARDS:
Store medication in a safe place where children and pets cannot get ahold of it.
Somewhat flammable; keep at a safe distance from heat.
If swallowed: Do NOT cause vomiting, unless instructed to do so by a health professional. Avoid giving anything by mouth if the person is not conscious. Seek immediate medical help.
If in eyes: Take off contact lenses and use water to flush the eyes for a minimum of 15 minutes. Consult a doctor if issues continue or develop.
If on skin: Use soap and water to wash affected area and apply moisturizer. Talk to a physician if irritation does not subside or worsens.
If inhaled: Place person in a well-ventilated room and seek immediate medical help. Mouth to mouth breathing may be necessary in case of respiratory failure. If the person has trouble breathing, provide them with oxygen.
Storage & Disposal
Storage: Store at controlled room temperature in a dry area.
Disposal: Contact a local waste agency for information regarding disposal of medical containers/substances.
How it Works
Allopurinol is a xanthine oxidase inhibitor, meaning that it stops uric acid from accumulating in the body, thus lowering the risk of urate stones forming.
Directions for use
Allopurinol can only be obtained with a prescription and should be administered as indicated by your vet. Give medication with a meal and provide your dog with plenty of water throughout treatment.
Dosage and administration:
Allopurinol is recommended at a dose of 5mg/lb. once daily.
The product contains 100mg or 300mg of allopurinol depending on the strength.
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